Relationship between total cholesterol and HDL ratio and Lipid Profile in predicting stroke in overweight apple and pear shape individuals

Abstract

Stroke is still an unresolved health problem. The Indonesian Ministry of Health obtained data that stroke turned out to be the most common cause of death in people over 45 years old, which amounted to 15.4 percent. Ischemic stroke has many risk factors, one of which is hypercholesterolemia. However, when viewed from an increase in the ratio of total cholesterol to HDL, this is a very strong predictor of stroke risk. The aim of this study was to evaluate the ratio of total cholesterol and HDL in individuals with apple and pear body shapes with overweight (BMI 25-30). Analytical observational research methods in 15 apple body shape patients and 15 pear body shape patients, then examined the levels of total cholesterol, triglycerides, LDL cholesterol, and HDL by colorimetric enzymatic end point method using a photometer. The results of the characteristics of respondents, aged 46-55 years, the most, namely 12/30 (40%). Based on gender, most were female as many as 24/30 (80%). The average total cholesterol level of apple shape is 225 mg/dL, and pear shape is 213.6 mg/dL. The average LDL cholesterol level of apple shape was 211 mg/dL and pear shape was 145 mg/dL. The average HDL cholesterol level of the apple shape was 44 mg/dL and the pear shape was 44.5 mg/dL. The average triglyceride level of the apple shape was 160 mg/dL, and the pear shape was 120.7 mg/dL. The average ratio of total cholesterol to HDL of the apple form was 5.8, and that of the pear form was 5.1. Spearman correlation test between the ratio of apple total cholesterol to HDL apple with total cholesterol p=0.000 (p<0.050), with triglycerides p=0.324 (p>0.050), with HDL p=0.055 (p>0.050), with LDL p=0.023 (p<0.050). The results of the ratio of pear total cholesterol to pear HDL with total cholesterol p=0.000 (p<0.050), with triglycerides p=0.021 (p<0.050), with HDL p=0.000 (P<0.050), with LDL p=0.000 (p<0.050). In conclusion, looking at the ratio of total cholesterol to HDL in apple body shape can predict the occurrence of stroke because it shows a risk in total cholesterol and LDL levels, while in pear body shape can predict the occurrence of stroke because all dyslipidemia parameters are abnormal.