Design And Formulation Of Sustained Release Drug Delivery System

Abstract

A medicine is released at a predetermined rate and with minimal adverse effects by means of a sustained release drug delivery system (SRDDS), which keeps the drug level constant for a predetermined amount of time. Oral drug administration is frequently considered the most common and patient-friendly mode of delivery. Developments in formulation technology, such as sustained release oral dosage forms or modified release dosage forms, have been widely accepted in comparison to conventional release formulations. A sustained release dosage form offers a longer duration of drug release, which improves patient adherence and increases the medicine's bioavailability. Increasing the duration of drug action, reducing side effects, reducing the frequency of dosing, lowering the required dose, and providing the shortest time by using the smallest quantity of drug administered by the most appropriate route were the main objectives of designing SR formulations in an effort to modify and improve the drug performance. SR dosage forms are made to quickly raise a drug's blood level to therapeutic concentrations through the use of an initial dose component, and then use a continuation portion to keep the level there for a predetermined amount of time. We will talk about in this essay. Overview of Drug Formulation for Sustained Release.