Evaluation of Serum Ferritin and Vitamin D and Their Correlation with TSH in Hypothyroid Patients in Basrah City

Abstract

Objective: The study was designed to estimate the serum Vitamin D3 and ferritin levels and their correlation with TSH level  in hypothyroid patients. 

Patients and Methods: This is a case control study in which sixty two hypothyroid patients and another age and sex -matched healthy individuals were included. . Serum Ferritin, Vitamin D3 (vit D) and thyroid stimulating hormone (TSH), were measured for all participants.  Statistical analysis for the collected data was done using SPSS software with appropriate statistical tests.

Results:  On   comparing   the   two   groups,   serum   Vit D level  and  Ferritin was significantly decreased in hypothyroid patients than that in the controls, P value < 0.001 and  < 0.01 respectively. Significant negative correlation was found between serum Vit D level (r= -0.43, P<0.05) and serum Ferritin ( r= -0.78 ,p <0.01 ) with TSH  where low levels of Vit D and ferritin were found in hypothyroidism.