Pharmacological and Natural Effects of In-Vitro Antioxidant Activity of Leucas aspera Leaf Extract

Abstract

Aim:The present study aimed to evaluate the in-vitro antioxidant activity of Leucas aspera leaf extract and to assess its pharmacological and natural therapeutic potential.

Introduction:Oxidative stress caused by free radicals plays a major role in the development of chronic diseases. Natural antioxidants from medicinal plants are gaining importance due to their safety and efficacy. Leucas aspera, traditionally used in herbal medicine, contains bioactive compounds that may contribute to its antioxidant properties.

Materials and Methods:Leaves of Leucas aspera were collected, dried, and extracted using ethanol. The antioxidant activity was assessed using DPPH and hydrogen peroxide scavenging assays at different concentrations (20–100 µg/mL). Ascorbic acid was used as the standard. Absorbance was measured spectrophotometrically, and percentage inhibition was calculated.

Results and Discussion:The extract demonstrated significant dose-dependent antioxidant activity in both assays. Although slightly lower than the standard, the extract showed considerable free radical scavenging ability. This activity is attributed to phytochemicals such as flavonoids and phenolic compounds. The findings support the plant’s pharmacological relevance and validate its traditional use.

Conclusion:Leucas aspera leaf extract exhibits promising antioxidant activity, indicating its potential as a natural therapeutic agent. Further studies are recommended to explore its clinical applications....