Impact Of Vitamin D Deficiency On Glycemic Control In Patients With Type 2 Diabetes Mellitus

Abstract

Vitamin D deficiency serves as one possible factor in treating both glucose metabolic disorders and insulin resistance development. Inadequate vitamin D levels in people with type 2 diabetes mellitus (T2DM) lead to poor glycemic control which advances their disease severely and produces medical complications. Thorough comprehension of the vitamin D relationship with biochemical markers is essential for developing complete patient management approaches for T2DM.

Objectives: Assess HbA1c levels to determine glycemic control in patients with type 2 diabetes mellitus and evaluate the impact of vitamin D deficiency on blood glucose regulation.

Study design: A prospective study.

Place and duration of study. Department of Diabetes and Endocrinology Lady reading hospital Peshawar from Jan 2023 to July 2023

Methods:

50 patients receiving treatment. Medical personnel at the clinic collected both HbA1c and serum 25-hydroxyvitamin D measurement data from patients participating in the study. Previous values defined the selection criteria to identify patients with vitamin D deficiency while classifying others with sufficient vitamin D levels. The study team determined both the mean value and standard deviation of patient age. Two statistical tests were employed for analysis which included independent t-tests with Pearson’s correlation while establishing the significance threshold at p<0.05.

Results:

average age amounted to 55.4 ± 9.2 years among 50 participants selected. Study showed that 68% of the studied participants demonstrated vitamin D deficiency. The patients with vitamin D deficiency had HbA1c values exceeding 8.2% ± 1.1% leading to a significant difference when compared to patients with sufficient vitamin D showing 7.4% ± 0.9% (p = 0.002). Study data demonstrated that patients with lower vitamin D levels presented decreased HbA1c levels through a negative correlation value (r = -0.36, p = 0.001).

Conclusion:

Type 2 diabetes patients with vitamin D deficiency show elevated rates of uncontrolled blood sugar. Regular vitamin D testing of diabetic patients will lead to improved disease management outcomes by way of optimization. Study that includes intervention protocols ought to study how vitamin D supplementation influences diabetes control processes.