To Investigate the Anti-Parkinson’s activity of Betulinic acid and Quercetin containing Phytoconstituents using animal model

Abstract

This research article presents a comparative study investigating the anti-Parkinson activity of two phytoconstituents: Betulinic acid and Quercetin. Parkinson's disease is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms, and the search for effective therapeutic agents is ongoing. This study aims to evaluate the potential neuroprotective effects of Betulinic acid and Quercetin, exploring their mechanisms of action and efficacy in mitigating Parkinsonian symptoms.Parkinson's disease (PD) remains an incurable neurodegenerative disorder, and the development of effective neuroprotective agents is crucial. This study investigates the anti-Parkinson potential of Betulinic acid, a triterpenoid, and Quercetin, a flavonoid, through in vitro and in vivo models. The compounds were analyzed for their antioxidant and neuroprotective effects, as well as for their ability to enhance motor function in a 6-OHDA-induced rat model. Spectroscopic analyses using UV-Vis and FTIR were conducted to understand the chemical properties of the compounds. Both Betulinic acid and Quercetin exhibited neuroprotective properties, suggesting their potential role in PD management.