Green synthesis and characterization of metallic nanoparticles of Aconitum heterophyllum as antifungal agents

Abstract

Nanotechnology has become one of the most auspicious technologies applied in all fields of science. Nanoparticles gain attention of researchers because they possess distinctive properties like their small size i.e. 1–100 nm large surface-to-volume ratio and high rate of reaction. Nanoparticles synthesis by physical, chemical and biological methods have their considerable applications in the biomedical and physiochemical areas. Green synthesis of metal nanoparticles are plant mediated and these are gaining more attention due to their easy, rapid and ecofriendly nature. Biomolecules present in the plant extract can be used to reduce metal ions to nanoparticles in a plant extract mediated process.  The  mono and Bi-Metallic nanoparticles were prepared from the plant extract of Aconitum heterophyllum. The synthesized Bi-Metallic nanoparticles were then characterized to their study. The gold, Silver and bimetallic nanoparticles showed that the effective antifungal achievement against C. albicans. The antifungal activity of the BMNPs was found to be improved in comparison to the AgNPs and AuNPs due to the additional properties of the silver nanoparticles present in the BMNPs