Quantitative Risk Assessment in Toxicology Methodology and Application

Abstract

Quantitative Risk Assessment (QRA) is a systematic approach to evaluating and quantifying risks associated with complex systems, processes, or environments. It integrates statistical analysis, mathematical modelling, and probabilistic techniques to estimate the likelihood and potential consequences of adverse events. Poison is defined as  the substance or Natural  or a Man – made  origin that through its chemical action usually kills, injures or impairs  the living organism, if ingested , breathed in, injected in to the body or absorbed through the skin.  The objective of QRA is to provide decision-makers with actionable insights to minimize risks, enhance safety, and optimize resource allocation. This methodology is widely applied across industries, including energy, manufacturing, transportation, and healthcare, to address uncertainties and ensure regulatory compliance. By leveraging data-driven models, QRA enables the identification of high-risk scenarios, the prioritization of mitigation strategies, and the development of contingency plans to safeguard operations and public welfare. These abstract  outlines  the core principles, methodologies, and applications of QRA, emphasizing its role in proactive risk management and resilience building. The assessment was conducted for 1 year with 918 population and this data is extracted from the Government General Hospitals of Guntur and Tenali and also from Retrospective data which is designed according to the WHO and Questionaries collected from studies of Authors. The result obtained from the Assessment was that the pesticides poison source is common among age groups of 20 – 40 years of males due to marital discord. This study cherishes about the risk analysis within the different category of individuals after consumption of poison.